Treatment 03
Peptide & NAD+ Protocols
Targeted peptides, NAD+ and immune support tuned to your laboratory panel.
How it works
NAD+ (nicotinamide adenine dinucleotide) is a molecule every cell uses to produce energy and repair DNA. Levels decline with age, which researchers link to some features of ageing.
NAD+ can be given directly by IV, or its precursors (such as nicotinamide riboside or NMN) can be taken by mouth to help the body make more.
Therapeutic peptides are short chains of amino acids that act as signals for specific processes — for example metabolism, sleep or tissue repair. We only prescribe peptides after reviewing your labs, and we are clear about which have strong human data and which do not.
How to prepare
- •Complete your baseline biomarker panel so dosing can be personalised.
- •Eat a light meal before an NAD+ infusion — an empty stomach makes nausea more likely.
- •Drink plenty of water the day before and the day of your infusion.
- •Tell us about all medications, especially blood pressure, diabetes or mood medications.
On the day
- •NAD+ infusions run slowly — usually 2–4 hours — because speed is the main cause of discomfort. We adjust the drip rate to how you feel.
- •Peptides are usually taught as small at-home injections or oral forms, with a nurse walking you through it.
Recovery & follow-up
- •No downtime. Many people feel tired immediately after an NAD+ infusion and more energetic in the following days, though experiences vary.
- •Follow-up labs at 8–12 weeks help decide whether to continue.
Possible side effects
More common, usually mild
- •During NAD+ infusion: chest tightness, flushing, nausea, cramping or headache — these usually settle quickly when the drip is slowed
- •Injection-site redness for peptides
- •Mild fatigue
Rare but important
- •Allergic reaction
- •Changes in blood pressure or blood sugar (we monitor where relevant)
- •Many peptides lack long-term human safety data — we will tell you which ones
Who may not be a candidate
- •Pregnancy or breastfeeding
- •Active cancer (for growth-related peptides)
- •Uncontrolled heart, liver or kidney disease
Your physician makes the final decision after reviewing your history. See our safety & regulation page.
Published research
A selection of studies. Research results describe groups of patients and don't guarantee individual outcomes.
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens CR et al., Nature Communications, 2018
A randomised crossover trial showing increased NAD+ levels and good tolerance, with possible blood pressure benefits.
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Yoshino M et al., Science, 2021
A 10-week randomised trial found improved muscle insulin sensitivity with NMN.
NAD+ metabolism and its roles in cellular processes during ageing
Covarrubias AJ et al., Nat Rev Mol Cell Biol, 2021
Review of how NAD+ declines with age and what that may mean for health.
Conditions where it may be considered
Questions about peptide & nad+ protocols?
A physician will review your history and tell you honestly whether it suits you.
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